Gene information
Official symbol LPAR1
Official full name lysophosphatidic acid receptor 1
Gene type protein-coding gene
Chromosome9q31.3
Alias symboledg-2; rec.1.3; vzg-1; Gpcr26; Mrec1.3; LPA1; GPR26
Previous symbolEDG2
Gene familyLysophosphatidic acid receptors
Resources
Entrez Gene 1902
HGNC HGNC:3166
Ensembl ENSG00000198121
Vega OTTHUMG00000020486
UCSC uc004bfb.4
GO terms: 34 records
GO Description Category LogP Number of genes Detail
GO:0005543 phospholipid binding GO Molecular Functions -6.61792344 45 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO Biological Processes -6.95524830 22 More
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway GO Biological Processes -11.6592522 24 More
GO:0007202 activation of phospholipase C activity GO Biological Processes -4.61361828 8 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0010975 regulation of neuron projection development GO Biological Processes -5.89330331 41 More
GO:0022604 regulation of cell morphogenesis GO Biological Processes -5.63620747 32 More
GO:0031344 regulation of cell projection organization GO Biological Processes -8.91314416 62 More
GO:0032231 regulation of actin filament bundle assembly GO Biological Processes -4.42971140 15 More
GO:0032956 regulation of actin cytoskeleton organization GO Biological Processes -4.25470878 32 More
GO:0032970 regulation of actin filament-based process GO Biological Processes -7.72273150 43 More
GO:0035023 regulation of Rho protein signal transduction GO Biological Processes -3.55619697 12 More
GO:0035025 positive regulation of Rho protein signal transduction GO Biological Processes -2.57451150 6 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0046578 regulation of Ras protein signal transduction GO Biological Processes -3.44587232 19 More
GO:0046579 positive regulation of Ras protein signal transduction GO Biological Processes -5.05172294 12 More
GO:0051056 regulation of small GTPase mediated signal transduction GO Biological Processes -3.71798673 14 More
GO:0051057 positive regulation of small GTPase mediated signal transduction GO Biological Processes -4.49369376 12 More
GO:0051129 negative regulation of cellular component organization GO Biological Processes -13.1016989 75 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway GO Biological Processes -4.39154198 8 More
GO:0051492 regulation of stress fiber assembly GO Biological Processes -3.91249954 13 More
GO:0051493 regulation of cytoskeleton organization GO Biological Processes -3.52271067 40 More
GO:0051495 positive regulation of cytoskeleton organization GO Biological Processes -3.67944181 20 More
GO:0110020 regulation of actomyosin structure organization GO Biological Processes -4.68299748 15 More
GO:0110053 regulation of actin filament organization GO Biological Processes -3.93783734 26 More
GO:0120035 regulation of plasma membrane bounded cell projection organization GO Biological Processes -8.54789693 60 More
GO:1902903 regulation of supramolecular fiber organization GO Biological Processes -5.63791156 37 More
GO:1902905 positive regulation of supramolecular fiber organization GO Biological Processes -5.32876142 22 More
KEGG pathways: 4 records
KEGG Description Category LogP Number of genes Detail
hsa04072 Phospholipase D signaling pathway KEGG Pathway -3.77257282 17 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
bms-986020 antagonist TTD view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg06148685 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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